# Big Dick Pills

> Men's health, sourced and straight


## Posts

- [The ED Treatment Evidence Card](https://bigdickpills.com/erectile-dysfunction/ed-evidence-card/): Every treatment in the AUA erectile dysfunction guideline, with the recommendation strength and evidence grade it actually carries. Zero statements rest on Grade A evidence.
- [Half of ED Treatment Pages Leave Out That the Treatment Is Investigational](https://bigdickpills.com/erectile-dysfunction/ed-treatment-claims-audit/): We coded 137 claims across 90 pages against the AUA guideline. Half omitted that shockwave, PRP and stem cell therapy are investigational, and commercial clinics omitted it four times as often as publishers.
- [Testosterone Injections vs Gel vs Pellets: What Actually Separates Them](https://bigdickpills.com/testosterone-male-vitality/testosterone-injection-vs-gel-vs-pellets/): Eight approved routes, side by side: dosing schedules, how flat each keeps your levels, which carries a boxed warning about your family, and which one may spare your sperm count.
- [Suicide in Men: The Numbers, the Warning Signs, and What Helps](https://bigdickpills.com/mental-health/suicide-in-men/): Men account for close to four in five suicide deaths. Why the gap exists, what it looks like from the outside, whether asking makes things worse, and what the evidence says actually helps.
- [Heat and Sperm: Saunas, Laptops and What the Evidence Shows](https://bigdickpills.com/low-semen-volume/heat-and-sperm/): Heat suppresses sperm production in experiments and the effect fully reverses. But in 3,041 couples, laptops, tight underwear and saunas showed no measurable effect on how quickly they conceived.
- [Varicocele: The Most Common Correctable Cause of Male Infertility](https://bigdickpills.com/low-semen-volume/varicocele/): Present in 15 percent of men and up to 44 percent of those with primary infertility. Repair reliably improves semen parameters. Whether it produces more babies is a genuinely open question.
- [Testicular Lumps: What Is Worth Checking, and What Happens Next](https://bigdickpills.com/general-health/testicular-lumps/): The most common solid cancer in young men, and the one where waiting costs the most. Five-year survival runs 99 percent localised and 72 percent once it has spread.
- [Which Cholesterol Number Actually Predicts a Heart Attack](https://bigdickpills.com/general-health/cholesterol-apob-lpa/): LDL-C measures cholesterol mass. ApoB counts particles. They usually agree, but one adult in five is discordant, and three independent methods say the particle count is the one that causes events.
- [PRP, Microneedling and Laser Caps: What the Evidence Actually Supports](https://bigdickpills.com/hair-loss/prp-microneedling-laser-hair/): Everything sold for hair loss beyond finasteride and minoxidil, sorted by what the trials support. Including why FDA cleared and FDA approved are not the same thing.
- [Dutasteride for Hair Loss: Stronger Than Finasteride, and Off-Label](https://bigdickpills.com/hair-loss/dutasteride-vs-finasteride/): Dutasteride blocks both forms of the enzyme that makes DHT. In the one large head-to-head trial it beat finasteride on hair count and width. In the United States it is approved for enlarged prostate, not hair.
- [When the Pills Do Not Work: Injections, Vacuum Devices and Implants](https://bigdickpills.com/erectile-dysfunction/when-pills-do-not-work/): Around a third of men do not respond to PDE5 inhibitors, but most of them were taking the drug wrong. For those who genuinely fail, injections, vacuum devices and implants all have real numbers behind them.
- [Erectile Dysfunction Is a Cardiovascular Symptom, and It Arrives First](https://bigdickpills.com/erectile-dysfunction/ed-cardiovascular-warning/): The arteries that fail first are the smallest ones. In men with confirmed coronary disease, two thirds developed erectile dysfunction first, a mean of 38.8 months before any cardiac symptom.
- [Semen Analysis: What Each Number on the Report Actually Means](https://bigdickpills.com/low-semen-volume/semen-analysis-results/): The WHO reference limits are not a line between healthy and unhealthy. They are the fifth percentile of men who conceived naturally within a year, which changes how every number on the report should be read.
- [Exercise for Depression: What 218 Trials Found, and What They Did Not](https://bigdickpills.com/mental-health/exercise-for-depression/): A BMJ network meta-analysis ranked walking, yoga, strength training and antidepressants against each other across 218 trials. Here are the effect sizes, what worked better in men, and why the authors rated their own confidence as low.
- [Do Penis Enlargement Pills Work? No, and Two Thirds Contain Prescription Drugs](https://bigdickpills.com/penis-enlargement/do-enlargement-pills-work/): No supplement has ever been shown to change penis size, and no mechanism exists by which one could. When researchers tested 102 products off the shelf, 67 percent contained undeclared prescription ED drugs.
- [Doxy-PEP: It Works, and the CDC Does Not Recommend It for Most Men](https://bigdickpills.com/sexually-transmitted-infections/doxy-pep/): A single 200 mg doxycycline dose within 72 hours of sex cut chlamydia and syphilis by 70 to 90 percent in randomised trials. Here is what the evidence shows, who the CDC recommends it for, and why heterosexual men are not on that list.
- [Oral Minoxidil for Hair Loss: As Good as the Foam, With Different Problems](https://bigdickpills.com/hair-loss/oral-minoxidil-for-hair-loss/): The only head-to-head trial in men found oral minoxidil 5 mg roughly equivalent to 5% topical over 24 weeks. Unwanted hair growth elsewhere ran at 49% against 25%. It is off-label everywhere, and a short list of men should not take it.
- [Testosterone Replacement: The Warning the FDA Removed, and the One It Added](https://bigdickpills.com/testosterone-male-vitality/testosterone-replacement-therapy/): TRAVERSE found no increase in heart attacks or strokes, and small real increases in atrial fibrillation, kidney injury and pulmonary embolism. In February 2025 the FDA dropped the cardiovascular boxed warning and added one about blood pressure.
- [Shockwave Therapy for ED: A Real Effect, Just Below What You Would Notice](https://bigdickpills.com/erectile-dysfunction/shockwave-therapy-for-ed/): Twenty-one randomised trials found a 3.89-point improvement in erectile function. The smallest change men actually notice is about 4 points. Nine of the trials were funded by the device makers, and the average course costs $3,400.
- [Viagra, Cialis and the Rest: You Are Choosing a Duration, Not a Strength](https://bigdickpills.com/erectile-dysfunction/which-pde5-inhibitor-to-choose/): Sixteen randomised trials in 5,189 men found no difference in how well tadalafil and sildenafil work. What separates the four PDE5 inhibitors is half-life, food, and which side effect you would rather have.
- [PSA Screening: The Numbers Behind a Decision Nobody Will Make For You](https://bigdickpills.com/general-health/psa-screening-decision/): Per 1,000 men screened: 1.3 prostate cancer deaths prevented, 100 diagnosed, about 50 left with sexual dysfunction. Why the recommendation is a conversation, and how to have it.
- [Alcohol and Men’s Health: What the 2025 Reviews Actually Found](https://bigdickpills.com/general-health/alcohol-and-mens-health/): Two federal reviews landed weeks apart and seemed to contradict each other, and then the dietary guidelines dropped their numeric limits. What the evidence says about alcohol, cancer, testosterone, erections and sleep.
- [Sleep Apnea in Men: The Condition Behind the Snoring](https://bigdickpills.com/general-health/sleep-apnea-men/): Around 80% of moderate-to-severe sleep apnea is never diagnosed. What it does to blood pressure, mood and erections, how to screen yourself in eight questions, and what treatment actually delivers.
- [The Health Checks Worth Having, by Age](https://bigdickpills.com/general-health/health-checks-by-age/): The annual physical, as a package, does not lower death rates. A short list of specific screens does. Here is that list, by age, with the evidence grade for each.
- [Vitamin D: What the Biggest Trial Actually Found](https://bigdickpills.com/general-health/vitamin-d-what-trials-show/): 25,871 people, 2,000 IU a day, five years. No reduction in cancer. No reduction in major cardiovascular events. And screening healthy adults is graded “we do not know.”
- [Does Testosterone Fix Low Mood and Low Energy?](https://bigdickpills.com/mental-health/testosterone-and-mood/): The trial designed specifically to test vitality found testosterone did not improve fatigue or low energy. The one thing it clearly improved was libido: the opposite of the pitch.
- [GLP-1s and Alcohol: The Craving Signal, and What the Trials Actually Show](https://bigdickpills.com/weight-metabolic/glp1-and-alcohol/): People on GLP-1s kept reporting they had lost interest in drinking. Two randomised trials have now tested it. The effect is real, the evidence is early, and the drug is not approved for this.
- [Pornography and Erectile Function: What the Evidence Actually Supports](https://bigdickpills.com/mental-health/porn-and-sexual-function/): No causal link has been demonstrated. What correlates is self-perceived problematic use, about 2 to 8% of users, not frequency. And the arrow may point the other way.
- [Who Actually Qualifies for a GLP-1?](https://bigdickpills.com/weight-metabolic/who-qualifies-glp1/): The BMI thresholds are specific, the contraindications are absolute, and the indications have expanded well beyond weight. What the label actually says, and the questions you should be asked before a prescription.
- [How Depression Actually Presents in Men](https://bigdickpills.com/mental-health/depression-in-men-symptoms/): The male suicide rate is nearly four times the female rate, and highest in men over 75. Yet men are diagnosed with depression less often. The presentation is a large part of why.
- [Strength Training and How Long You Live: The Dose Is Smaller Than You Think](https://bigdickpills.com/general-health/strength-training-mortality/): A meta-analysis found any resistance training cut all-cause mortality 15%, with the maximum benefit at about 60 minutes a week. More was not better. Combined with cardio, the reduction reached 40%.
- [Antidepressants and Sexual Side Effects: The Numbers Nobody Quotes](https://bigdickpills.com/mental-health/ssri-sexual-side-effects/): Asked systematically, 84.5% of men on antidepressants report sexual dysfunction. Left to volunteer it, 42.5% do. Three management strategies have randomised evidence.
- [Tirzepatide vs Semaglutide: What the Head-to-Head Trial Found](https://bigdickpills.com/weight-metabolic/tirzepatide-vs-semaglutide/): 751 adults, 72 weeks, randomised directly against each other. Tirzepatide produced 20.2% weight loss against semaglutide’s 13.7%, and men lost about 6% less than women on both.
- [GLP-1 Side Effects: The Real Rates, and Which Ones Actually Matter](https://bigdickpills.com/weight-metabolic/glp1-side-effects/): Nausea affects 44% of people on semaglutide, not the handful the advertising implies. Here are the label rates, which effects are merely unpleasant, and the two that mean stop and call someone.
- [Compounded Semaglutide: What You Are Actually Buying](https://bigdickpills.com/weight-metabolic/compounded-semaglutide-risks/): The shortage ended and the legal basis for compounding copies expired in 2025. The FDA has logged 990 adverse event reports for compounded semaglutide, and says they are underreported.
- [Colorectal Screening Starts at 45 Now, Not 50](https://bigdickpills.com/general-health/colorectal-screening-45/): The start age moved in 2021 because incidence in adults aged 40 to 49 rose almost 15%. There are six approved ways to screen, and the best one is the one you will actually do.
- [Blood Pressure: The Highest-Value Number in Men’s Health](https://bigdickpills.com/general-health/blood-pressure-men/): It is the only Grade A screen that applies to every adult from 18, it causes no symptoms until it causes a stroke, and the trial that tested treating it harder was stopped early for benefit.
- [Do GLP-1s Cost You Muscle? What the Body Composition Data Show](https://bigdickpills.com/weight-metabolic/glp1-muscle-loss/): A quarter to a third of the weight lost is lean tissue, proportionate to any large weight loss, not selective muscle wasting. But 5.6 kg is still 5.6 kg, and it does not come back on its own.
- [Hair Transplants: What to Understand Before You Book](https://bigdickpills.com/hair-loss/hair-transplant-what-to-know/): A transplant moves hair. It does not create it, and it does not stop the loss continuing around it, which is why the men with the worst results are usually the ones who stopped the drugs.
- [The Shedding Phase: Why Hair Treatment Makes Things Worse First](https://bigdickpills.com/hair-loss/hair-loss-shedding-phase/): Men start minoxidil, shed heavily around month two or three, conclude it is destroying their hair, and quit, right before it starts working. Here is what is actually happening.
- [What Happens When You Stop a GLP-1](https://bigdickpills.com/weight-metabolic/stopping-glp1-weight-regain/): Participants who lost 17.3% regained about two-thirds of it within a year of stopping, and blood pressure returned to baseline. Net loss was still 5.6%. What that means in practice.
- [Finasteride Side Effects: An Honest Account of a Contested Literature](https://bigdickpills.com/hair-loss/finasteride-side-effects/): Trials report sexual side effects in 8.7% on finasteride against 5.1% on placebo. But when men were told to expect them, 43.6% reported them, against 14.3% of men who were not told.
- [GLP-1 Weight Loss Drugs: What the Trials Actually Show](https://bigdickpills.com/weight-metabolic/glp1-weight-loss-what-trials-show/): Tirzepatide beat semaglutide 20.2% to 13.7% head to head. Semaglutide cut cardiac events by 20%. And in the largest trial, men lost 7.5% of body weight where women lost 11.1%.
- [Telling a Partner You Have an STI](https://bigdickpills.com/sexually-transmitted-infections/talk-partner-sti/): Health departments will make the call for you, without naming you. And expedited partner therapy is permissible in 47 states, your clinician can give you treatment to hand over.
- [Do Condoms Protect Against STIs? It Depends Which One](https://bigdickpills.com/sexually-transmitted-infections/do-condoms-protect-against-sti/): Excellent against infections carried in fluids, 71 to 80% against HIV. Only partial against ones spread by skin contact, because they protect the area they cover and no more.
- [How Often Should You Get Tested for STIs? The CDC’s Actual Schedule](https://bigdickpills.com/sexually-transmitted-infections/how-often-tested-stis/): HIV once for every adult 13 to 64, hepatitis C once for every adult over 18, and at least annually for men who have sex with men. Plus the reason a urine test is not enough.
- [How Do You Know If You Have an STI? Usually, You Do Not](https://bigdickpills.com/sexually-transmitted-infections/how-know-have-sti-symptoms/): Most sexually transmitted infections produce no symptoms at all. Testing is the only way to know, and it has to be timed correctly, or a negative result means nothing.
- [Size and Confidence: What the Measurements Actually Say](https://bigdickpills.com/penis-enlargement/size-and-confidence/): Mean erect length across 15,521 professionally measured men was 13.12 cm. Four men in five fall inside a band an inch and a half wide. And 55% of men are satisfied, against 85% of women.
- [Bigger Without Surgery: What Extenders and Pumps Actually Achieve](https://bigdickpills.com/penis-enlargement/bigger-without-surgery/): Traction devices produced under 2 cm of flaccid length after months of daily wear, on evidence the reviewers rated poor. Pumps treat erectile dysfunction, not size.
- [Jelqing and Penis Exercises: How Long Until Results?](https://bigdickpills.com/penis-enlargement/penis-exercises-how-long-results/): Every timeline you have read was invented. Manual exercises do not appear in the systematic review of enlargement interventions, because there were no studies to include.
- [Does Penis Enlargement Work? What the Evidence Actually Shows](https://bigdickpills.com/penis-enlargement/does-it-work/): A systematic review of 17 studies concluded these interventions should remain a last option, considered unethical outside clinical trials. The one thing that did work was counselling.
- [Exercise and Diet for Erections: What the Trials Actually Show](https://bigdickpills.com/erectile-dysfunction/exercise-diet-improve-erections/): Aerobic exercise improved erectile function by 4.9 points in men with severe dysfunction: within range of a prescription drug. The dose, the weight-loss trial, and the honest limits.
- [Viagra Versus “Natural” ED Fixes: The Difference Is Not What You Think](https://bigdickpills.com/erectile-dysfunction/difference-viagra-natural-ed-fixes/): The FDA found hidden sildenafil in 47% of the adulterated sexual enhancement supplements it flagged. The reason a natural pill sometimes works is often that it is not natural.
- [Physical or Psychological? How to Tell Which Erection Problem You Have](https://bigdickpills.com/erectile-dysfunction/erection-problem-physical-psychological/): Sudden onset with morning erections preserved points one way. Gradual onset with them fading points the other, and that version is telling you something about your arteries.
- [Trouble Getting or Staying Hard: What It Means, and What Works](https://bigdickpills.com/erectile-dysfunction/struggling-get-stay-hard/): Penile arteries are 1 to 2 mm across; coronary arteries are 3 to 4 mm. That is why erectile dysfunction usually arrives years before heart symptoms, and why the work-up matters as much as the treatment.
- [Do Testosterone Boosters Work? What Two Decades of Testing Found](https://bigdickpills.com/testosterone-male-vitality/do-t-boosters-work-or-scam/): A systematic review of 52 studies covering 27 ingredients found most fail to raise total testosterone. Which ones showed something, which did not, and why the category exists.
- [Raising Testosterone Naturally: What Actually Works](https://bigdickpills.com/testosterone-male-vitality/natural-ways-boost/): Weight loss is the largest lever by a distance, and sleep is second. Resistance training, despite its reputation, showed no effect on resting testosterone in a meta-analysis of 22 studies.
- [Testosterone, Libido and Erections: What It Fixes and What It Does Not](https://bigdickpills.com/testosterone-male-vitality/low-sex-drive-and-performance/): Testosterone drives desire. Erections are mostly blood flow. Adding testosterone to an ED drug helps only below about 288 ng/dL, above that the benefit stops being detectable.
- [Low Testosterone: What the Number Means, and How It Is Properly Diagnosed](https://bigdickpills.com/testosterone-male-vitality/low-t-levels/): The diagnosis needs two early-morning blood draws under 300 ng/dL plus symptoms. What treatment improved in the largest trial, what it did not, and the fertility consequence that rarely comes up.
- [Breathing, Focus and Performance Anxiety: What Is Actually Known](https://bigdickpills.com/premature-ejaculation/breathing-mental-focus-last-longer/): The anxiety is real and documented. The specific breathing techniques sold as a cure have never been tested in a controlled trial. Both of those things are true at once.
- [When Finishing Early Is Worth Seeing a Doctor About](https://bigdickpills.com/premature-ejaculation/when-talk-doctor-finishing-early/): If it is new rather than lifelong, there is a real chance of a findable cause. What the work-up involves, what the prescription options are, and why tramadol sits second-line.
- [Pelvic Floor Exercises for Premature Ejaculation: What the Study Actually Did](https://bigdickpills.com/premature-ejaculation/pelvic-floor-exercises-last-longer/): The famous 82.5% figure came from thirty-six supervised clinic sessions with electrical stimulation and biofeedback, in a study with no control group. What that means for doing them at home.
- [Stop-Start and the Squeeze Technique: What the Trials Actually Found](https://bigdickpills.com/premature-ejaculation/natural-control-methods-explained/): Ten randomised trials, 521 men. Two found large gains, two found nothing at all. What the behavioural techniques are, how they are done, and how much of the evidence holds up.
- [Finishing Too Fast: What Counts as Premature, and What Actually Helps](https://bigdickpills.com/premature-ejaculation/finish-too-fast-how-last-longer/): The median man lasts 5.4 minutes, not the number you have in your head. What premature ejaculation actually means clinically, and which treatments have real trial evidence behind them.
- [Finasteride and Minoxidil: What the Trials Actually Show](https://bigdickpills.com/hair-loss/finasteride-minoxidil-what-works/): The two hair loss drugs with real evidence behind them, how much hair they actually keep, and what the side-effect numbers say once you read the label rather than the forum.
- [How to Improve Sperm Health Naturally: What Has Evidence Behind It](https://bigdickpills.com/low-semen-volume/naturally-boost-sperm-health-volume/): The lifestyle changes with real evidence for sperm health, the ones with weak evidence, and the honest limits of what any of it does for semen volume.
- [Do Stress and Poor Sleep Affect How Much You Ejaculate?](https://bigdickpills.com/low-semen-volume/stress-sleep-affect-ejaculation-amount/): Sleep and stress are linked to sperm quality: but the evidence for semen volume specifically points somewhere different. What the studies actually measured.
- [Do Supplements Increase Semen Volume? What the Trials Actually Found](https://bigdickpills.com/low-semen-volume/foods-supplements-increase-sperm-volume/): Large randomized trials have tested the supplements sold for semen volume and sperm health. Here is what they found, including the one that made things worse.
- [Low Semen Volume vs Low Sperm Count: Causes of Each, and Why the Difference Matters](https://bigdickpills.com/low-semen-volume/reasons-low-sperm-count/): Low volume and low sperm count are different conditions with different causes and different workups. Here is how to tell which one you have.

## Pages

- [Supplement & Claim Checker: Is It on the FDA's Tainted Product List?](https://bigdickpills.com/supplement-checker/): Search the FDA's sexual-enhancement tainted-product list by name. See what hidden ingredient FDA's lab found, and when — and read why not finding a product here does not mean it's safe.
- [FDA Tainted Sexual-Enhancement Products Dataset: 432 Products the FDA Found Hidden Drugs In](https://bigdickpills.com/data/fda-tainted-sexual-enhancement-products/): Every product notification on the FDA's sexual-enhancement and energy tainted-product list, going back to 2012: product name, date, and the undeclared drug ingredient FDA's lab found. 432 products so far, sourced and linked to the original FDA notification. CSV and JSON, CC BY 4.0.
- [Testosterone Formulations Dataset: All 8 US-Approved Routes by Schedule, Level Pattern and Risk](https://bigdickpills.com/data/testosterone-formulations/): The 8 testosterone replacement routes approved in the United States (injections, gel, patch, nasal, oral, pellets) side by side: dosing schedule, how flat the levels stay, and each label's main catch. From prescribing information. CSV and JSON, CC BY 4.0.
- [PDE5 Inhibitors Compared Dataset: Sildenafil, Tadalafil, Vardenafil and Avanafil by Dose, Onset and Half-Life](https://bigdickpills.com/data/pde5-inhibitors-compared/): The four approved oral ED tablets side by side from their FDA labels: usual doses, onset, half-life and useful window, plus the head-to-head trial result (no efficacy difference). CSV and JSON, CC BY 4.0.
- [ED Treatment Claims Audit Dataset: 137 Claims on 65 Sites, Coded Against the AUA Guideline](https://bigdickpills.com/data/ed-treatment-claims-audit/): Per-claim coding table from the September 2026 audit: 137 claims about shockwave, PRP and stem cell therapy for ED across 90 pages, each coded Conveys / Omits / Neutral on whether the page says the therapy is investigational. 49.6% omitted it. CSV and JSON, CC BY 4.0.
- [AUA Erectile Dysfunction Guideline Dataset: All 25 Statements, With Strength and Evidence Grade](https://bigdickpills.com/data/aua-ed-guideline-evidence/): Every statement in the American Urological Association's erectile dysfunction guideline as a table: treatment, what the guideline says, recommendation strength and evidence grade (A/B/C or ungraded). 0 rest on Grade A. CSV and JSON, CC BY 4.0.
- [Data: Open Datasets From Big Dick Pills](https://bigdickpills.com/data/): Open datasets from Big Dick Pills: the AUA ED guideline graded statement by statement, a 137-claim audit of ED treatment pages, label-sourced comparisons of PDE5 inhibitors and testosterone formulations, and the FDA's tainted sexual-enhancement product notifications. CSV and JSON, CC BY 4.0.
- [Corrections](https://bigdickpills.com/corrections/): If something here is wrong, I want to know, and I would rather you saw the repair than trusted the promise. This page is the public record. Every substantive correction made to this site is listed below, with what was wrong, what it says now, and when it changed. Nothing is quietly deleted. What counts […]
- [All Articles](https://bigdickpills.com/blog/)
- [About Will Preston](https://bigdickpills.com/about/): Who writes this site, why it has that name, and why the byline is a pen name.
- [Men’s Health, Sourced and Straight](https://bigdickpills.com/): Evidence-based information on erectile dysfunction, testosterone, fertility and sexual health. Every claim cited. Nothing for sale.
- [How This Site Makes Money](https://bigdickpills.com/affiliate-disclosure/): How this site makes money, what that pays for, and what it does not buy.
- [Medical Disclaimer](https://bigdickpills.com/medical-disclaimer/): This site publishes health information, not medical advice. What that distinction means for you.
- [Editorial Standards](https://bigdickpills.com/editorial-standards/): How we research, source, and update the health information on this site, and what we won't do.
- [Privacy Policy](https://bigdickpills.com/privacy-policy/): What this site collects, what it deliberately does not, and who ever sees it.
- [Contact](https://bigdickpills.com/contact/): I’m Will Preston. I research and write everything on this site. If you want to reach me, the address below is the only one: there’s no team, no support desk, and no form that routes into a CRM. bill@bigdickpills.com What I want to hear about Corrections. If a claim on this site is wrong, out […]

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